Is there an association between previous migraine and cryptogenic TIA or ischemic stroke in older patients?

Presenter: Sammy Ming Hin Lee, MD, PhD

Link to Presentation: Journal Club 28 June 2016

Clinical Question: 

Is there an association between previous migraine and cryptogenic TIA or ischemic stroke in older patients?

Journal Club Article: 

Li, L. et al.  Age-specific association of migraine with cryptogenic TIA and stroke: Population-based study.  Neurology, 2015 Oct 27;85(17):1444-51.  PDF here: Li, et al

 

Methodology:

Consecutive cases with a first TIA or ischemic stroke in the first 10 years (April 1, 2002, to March 31, 2012) of the Oxford Vascular Study (OXVASC) were studied.

Study Conclusions:

In this population-based study of stroke etiology stratified by age, migraine was most strongly associated with cryptogenic TIA and ischemic stroke, particularly at older ages, suggesting a causal role or a shared etiology.

The Journal Club’s discussion of pros and cons of the study are found in the above Presentation Link.

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